Sentence examples for mutations with effects from inspiring English sources

However, even at low effective population size (N e = 7.5), mutations with effects on the order of the reciprocal of the effective size will be selected.

This sacrificed statistical power for any mutations with effects confounded with the population structure in this study.

Purifying selection is weaker for mutations with effects that are only mildly deleterious.

However, because the vast majority of mutations with effects on fitness are deleterious, special conditions are required for positive selection to promote increases in the mutation rate.

Did it involve the rapid fixation of one or more mutations with effects of a magnitude similar to the p.D273RfsX13 MSTN mutation?

Instead, under these conditions, selection for increased survival on Bt plants typically favors single mutations with effects large enough to boost survival on Bt plants (Fig. 1A).

This finding suggests that deleterious mutations with effect sizes greater than the mean would not have accumulated very efficiently.

Furthermore, the 'selective sieve' (Morgan 2001) that is present during mitotic cell divisions will preferentially allow recessive alleles with large effect on zygotes or seeds to pass on while eliminating deleterious dominant mutations with effect on mature cell lines.

Studies on compensatory mutations in macromolecules, mutations that compensate for the fitness effects of previous mutations with negative effects, show that fitness neutrality is not a prerequisite for a population's genetic change on a genotype network [ 17, 18].

Furthermore, it has been argued that the ability for a population to purge deleterious homozygous mutations is greater for large effect and/or lethal mutations and is not as effective for mutations with minor effects [ 26].

Therefore, this approach is more likely to find beneficial mutations with large effects than those with small effects.