Sentence examples for mutations will allow from inspiring English sources
Identifying these mutations will allow an easy targeting of the SCD syndrome.
Further functional analysis of the common mtDNA mutations will allow us to better understand their specific role in cancer progression and chemoresistance.
Identification of individuals with type I CFI mutations will allow targeting of those most likely to benefit from complement inhibitory therapy and pave the way for personalized medicine in AMD (44).
The evidence from histological studies for the association of specific types of tumour with BRCA1 and BRCA2 mutations will allow a directed approach to genetic testing of breast cancer families.
It is therefore logical to hypothesize that the virus evolving in a given population will carry signature mutations that will allow it to survive in that particular host milieu.
Apparently, the αT349R mutation would place extra positive charge relatively close to Pi, and double mutation αT349R/βR182A will allow the αT349R mutant Arg to fit into the large "hole" generated by the βAla-182 mutation.
Simple models that set up an arms race between host and parasite loci predict that increased mutation rate will allow parasites to "chase" the host's changing defences [ 1].
Conversely, the transformation of a protooncogene (a gene that participates in a cell-growth pathway) into an oncogene (a protein that can induce cancer on animals) requires a gain-of-function mutation that will allow its permanent activation.
The identification of additional mutation-positive cases will allow to more precisely assess the contribution of CDKN1B mutations to the MEN4 syndrome.
Functional analysis of such mutations as demonstrated here will allow to determine the putative pathogenic nature of some of these mutations as more extensively discussed in (Guerreiro et al, 2010).
Should mutations be identified, this will allow us to offer relatives from these high-risk families additional genetic testing, and help identify those women who may also be at risk of developing breast cancer due to a mutation.
