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At high doses, ethyl mesylate has been shown to cause cancer in animals, and at lower levels it can cause genetic mutations, which means children and fetuses are particularly vulnerable.
Neither of the girls' parents had the mutations, which means that the mutation was not inherited, but had occurred spontaneously.
Most life-extension effects have been found to result from hypomorphic (reduction in gene (protein, RNA) expression, but not a complete loss) or nullomorphic (complete loss of function) mutations, which means that the wild-type gene shortens life span [ 39].
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These athletes have a genetic condition where the testosterone receptor has a mutation which means they are unable to obtain any benefit from it (or from injected testosterone).
The first one is frequency based in which each gene is awarded a rank in accordance with the occurence of mutation which means the higher the frequency of occurence of mutations on that gene, the higher rank will be awarded.
When the fruits starting to ripening, the Ccs gene begins to be expressed, which catalyzes zeaxanthin to be transformed into capsanthin [ 10].The yellow color in pepper fruits is due to a Ccs gene deletion or Ccs mutation, which means that capsanthin cannot be synthesized [ 11].
These breeds have a genetic mutation which means the drug can penetrate the blood brain barrier, cause CNS toxicity, non-reversible coma, and possibly death.
A blood test had shown that I was carrying the BRCA2 mutation, which meant I had an 80% chance of getting breast or ovarian cancer at some point in my life.
As for the standard SMM model, the scaling relation depends only on ratio of the two mutation rates, which means that our scaling method works equally well for these models.
Tumors are almost never uniform; one may have five mutations or fifty, which means, essentially, that every cancer is a specific, personal disease.
Note that the difference in the responses between the two mutations is small, which means that a little alternation is capable of producing the targeted behavior.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com