Sentence examples for mutations which encode from inspiring English sources

Ras mutations which encode for constitutively activated proteins are found in 30% of human cancers.

A number of clinically relevant POMGnT1 mutations have been described in the literature, ranging from nonsense/frameshift mutations to approximately 14 different point mutations which encode full-length proteins, as well as truncated proteins caused by nonsense mutations within the C-terminal region [ 22, 31– 33, 46– 53].

Clcn7 gene mutations, which encodes for the CIC-7chloride channel, causes LSD.

The underlying mechanism of inflammation in FMF is thought to be the uncontrolled release of IL-1β due to MEFV gene mutation, which encodes the protein pyrin.

The transmembrane protein Vangl2 is expressed in the embryonic neural tube (7) and the mouse Loop-tail (Lp) allele comprises a Vangl2 mutation which encodes an unstable and mislocalized, and thus non-functional, protein product (8, 9).

For example the rrm3 Δ mutation, which encodes a DNA helicase that helps replisome progression in some regions of the genome (Ivessa et al. 2002, 2003), seems to cause particularly poor growth in the Pol ε mutants but less so in Pol α or Pol δ mutants.

Heterozygous usually autosomal-dominant activating mutautosomal-dominant activatinge the Kir6.2 subunit of the ATP-potassiumutationschannel, cause the majoriny of cases (2).

By screening a transposon mutant library of P. aeruginosa, we found that mutation of spuDEFGH, which encode a major spermidine uptake system, abolished the expression of the exsCEBA operon that codes for key T3SS regulators under inducing conditions (low calcium).

Originally, Tartaglia et al. identified missense mutation in PTPN11, which encode Src homology 2-domain phosphatase 2 (SHP-2) in 50% of individuals with NS [ 3].

The high HIV mutation rate results in novel variants which encode point mutations within CTL epitopes and escape recognition by specific T cells.

The disease is caused by mutations in NPHP1-9 genes, which encode the nephrocystins, proteins localized to cell cell junctions and centrosome/primary cilia.