In other words, some mutations which emerged in plasma were not found in PBMCs.
Additional themes which emerged are also discussed.
In addition, nucleoside and NNRTI resistance mutations can interact to affect HIV replication efficiency; these interactions may influence which mutations emerge during treatment failure.
On the other hand, escape mutations typically come at a cost to the virus by decreasing the viral replicative capacity [23], [24], although compensatory mutations which partially restore the fitness can emerge [25], [26] (see also Fig. 1C).
In non-fermenting GNB such as Pseudomonas aeruginosa, Acinetobacter baumannii and Stenotrophomonas maltophilia, multidrug resistance may emerge following the sole occurrence of sequential chromosomal mutations, which may lead to the overproduction of intrinsic beta-lactamases, hyper-expression of efflux pumps, target modifications and permeability alterations.
In the second, it acquired the five extra mutations, which Dr. Thornton called "restrictive" mutations.
Then it was the turn of deleterious mutations, which became trendy in the late 1980s and early 1990s.
The 14 mutations which predict aggressive prostate cancer are in eight genes, which include BRCA1 and BRCA2.
Neither of the girls' parents had the mutations, which means that the mutation was not inherited, but had occurred spontaneously.
"Of course, everybody carries what we call 'silent mutations,' which are completely harmless.
