Sentence examples for mutations which confer from inspiring English sources

These risk calculators, and the task force's measured recommendations, do not apply to women who have the BRCA-1 or BRCA-2 gene mutations, which confer an extremely high risk of developing breast cancer, and they don't apply to women younger than 35 or older than 79.

These have identified genetic mutations which confer either hypersensitivity or resistance to ethanol.

Thus, the mutations which confer the fluorescent phenotype are point mutations of the TAG stop codon.

In general, the mutations which confer resistance to the largest number of drugs in the combination are the ones which define how likely it is that the protocol fails.

The lethal phenotype caused by injection of young w1118 males with 3×104 TCID50 at 25°C was robust and sensitive enough to be used an assay for the identification of mutations which confer increased susceptibility or resistance to CrPV infection.

It proposed that environmental conditions trigger non-specific mutations which confer adaptation to the stress-inducing factors [ 59].

Analysis of protease susceptibility, however, revealed that mutations, which conferred protease resistance, simultaneously diminish thrombin inhibition activity.

Cell-block processing allowed for the performance of EGFR mutational analysis in 60% of our patients with a diagnosis of metastatic adenocarcinoma and in two of them confirmed the presence of an EGFR mutation, which confer sensitivity to the tyrosine kinase inhibitors gefitinib and erlotinib [ 20].

The doctor searched for and found a donor who had a rare genetic mutation which confers immunity to HIV infection by disabling a protein on cell surfaces to which the virus attaches itself in order to gain entry to a cell.After the transplant, the virus seemed to disappear from Mr Brown's body.

However, the extent to which [11C]erlotinib PET could identify NSCLC tumors that harbor other commonly detected TK mutations, such as the activating exon 21 L858R point mutation and the T790M gate-keeper mutation, which confers resistance to TKI therapy, has not been reported.

To investigate specific inhibition of drug-resistant HIV-1 by RNA interference, we designed siRNA molecules that recognize codons 181 188 of the reverse transcriptase (RT) gene of wild-type HIV-1 and HIV-1 carrying the M184V mutation, which confers high-level resistance to the RT inhibitor lamivudine.