Sentence examples for mutations where the from inspiring English sources

A highly conserved 81 base pair core region among the β subunit of prokaryotes harbors most of the point mutations leading to rifamycin-resistant (RifR) mutations, where the majority of the clinically relevant MTB RifR mutations result from amino acid substitutions of one of the following three amino acids: βAsp435, βHis445, and βSer450 (MTB numbering).

Mr Gire and a colleague began to tease out the letters of each virus sample's genetic code with some of the most advanced technology yet devised for the task; before long, half of Mr Gire's 30-strong laboratory had volunteered to help.Then, those sequences of genetic letters were fed into a computer model that looks for hints of mutations where the letters differ.

Namely, we formulate a continuous time, discrete state-space birth-death process (with or without mutations), where the rates of cell divisions and cell death are l and d respectively, and where cells enter the state of quiescence with a rate α and wake up from quiescence with a rate β.

For the two mutations where the initial screen suggested a measurable fitness deficit, lamB and rplS syn, all competitions were carried out in quadruplicate.

9 This is important when dealing with somatic mutations, where the percentage of mutant alleles in the DNA analysed can be very low in some cases.

Only small and very recent detailed reports assessed the effect of KRAS mutations where the codon 12 and 13 were analyzed separately [ 18, 19, 21].

A total of 14 had a mutation where the arginine was mutated to a histidine (c.845G>A, Arg282His); in the remaining 7, the arginine was mutated to cysteine (c.844C>T, Arg282Cys).

At each step, the best spike train survives and the other 100 are replaced using breeding and mutation, where the probability of a spike train being a parent is determined by its value of ℰ. Fig. 4 A cartoon representation of the space of functions.

More specifically, by representing candidate solutions to an optimisation problem in terms of individuals in a population, and having the population evolve using operations such as recombination and mutation (where the better performing individuals have a higher probability to reproduce), good solutions can be found to problems in a variety of domains, including criminology.

For the Dp140 isoform the presence or absence of its unique first coding exon and adjacent 5' promoter region was determined in all patients with a deletion mutation where the last deleted exon was exon 44, or the first deleted exon was exon 45.

An example of this was previously reported for the 6174delT mutation where the wild type allele was not amplified[ 12].