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Full mutations when transmitted by a female usually remain in the full mutation range.
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In addition to the Δrep allele, we tested several other ICR alleles for their ability to influence AK029869 imprinting, when transmitted as germ line mutations.
Fourteen demonstrated complete lethality in trans to Top2 Df9043, while the remaining mutation, Top2, showed 25% of the expected class when transmitted maternally and 87% when transmitted paternally.
Premutations are unstable and, when transmitted by a female, have a risk of expanding to a full mutation.
When transmitted by men, premutation shows increased instability toward expansion, even reaching the full mutation in a single generation, while protomutation almost invariably results in a large increase in repeat copy number [ 32, 41, 50– 50].
They are highly contagious when transmitted sexually.
Apathy and outrage sound identical when transmitted as silence.
It was only considered to reflect the way phenotypes were observed when transmitted between generations.
In Drosophila, the Y chromosome is differently modified when transmitted through the male and female germlines.
This is problematic when transmitting data via URLs.
The imprinted nature of RasGrf1 was further validated by the characterization of two nonsense mutations that when paternally transmitted caused reduced body weight during postnatal development [ 47].
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