Sentence examples for mutations when accrued from inspiring English sources

Approximately 25% of classic CS cases carry pathogenic PTEN mutations when accrued prospectively from the community.

In any case, such competition may be more common in the later stages of an experiment when multiple mutations have accrued [ 38].

Mutator mutations are assumed to be selectively neutral in the model; mutator mutations therefore accrue only through genetic drift or by hitchhiking on the most aggressive clones.

This time-delay was due to the time taken for mutator mutations to accrue by drift, or by hitchhiking, in the most aggressive subclones.

Indeed, driver mutations always accrued more quickly than mutator mutations, and the difference in rate was increased as the selective benefit of additional driver mutations increased (Fig. 5D).

Some of these copy-number changes may be compensatory, serving to ameliorate the negative fitness consequences of deleterious mutations accrued during the mutation accumulation phase of the experiment.

Thus, driver mutations accrued faster as the deleteriousness of housekeeper mutations was increased (Fig. 6D).

This indicates a genomic rearrangement or other mutations accrued in this phenotypic selection process.

H5N1 continues to circulate and diversify [2] and some mutations accrued since 2004 may enhance the virus' capacity for receptor switching [21].

We then hypothesized that less obvious functional divergence may be observed by analyzing mutations accrued in protein coding sequences.

Passenger mutations accrued in a linear fashion with respect to time but typically remained at low numbers in the tumour (Fig. 2C,F).