Sentence examples for mutations were validated from inspiring English sources
PIK3CA C420R and E418K and GATA3 K358fs mutations were validated by cycle sequencing.
Mutations were validated by ddPCR and cycle sequencing (Table S4) with identified VAFs similar to those found by sequencing, demonstrating high reproducibility of the data.
The introduced mutations were validated in-house and in 44 laboratories using various techniques, including next-generation sequencing.
The deleterious effects of these human COQ6 mutations were validated by their lack of complementation in coq6-deficient yeast.
Presence and type of mutations were validated by sequencing in 111 samples.
Mutations were validated by Sanger sequencing.
The robustness and statistical significance of the clusters and mutations was validated by averaging over ten 2 1 training/test bootstrapped datasets on which we repeated the complete clustering analysis.
These mutations are validated biomarkers for resistance to anti-epidermal growth factor receptor (EGFR) therapy in patients with mCRC [ 6- 11].
The analytical sensitivity of MPP for EGFR mutations was validated to a limit of detection of 1.25%.
Subsequently, the HRMA of KRAS mutations was validated in a set of DNA obtained from several cell lines (Table 1) with or without a known KRAS mutation.
The association between low RIC8A expression and TP53 mutations was validated by the analysis using qRT-PCR of 38 tumours from the early stage cohort [ 7].
