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Additionally, 91% of patients at high risk for MDR-TB, with line probe assay results consistent with rpoB mutations, were ultimately confirmed as having MDR-TB.
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Most pathological gene mutations are ultimately involved in the process of energy production in the mitochondria.
Here, we present the results of a massively parallel experiment designed to measure the full spectrum of possible fates of new beneficial mutations in hundreds of experimental yeast populations, whether these mutations are ultimately successful or not.
Phenomena like the existence of the genetic code, the fact that mutation is ultimately a creative and not a destructive force in evolution (the mutation rate is not too high and not too low), the existence of the gene duplication machinery, etc., are much better understood from the perspective of the mutational writing phenotype.
MuTect and SomaticSniper had comparable sensitivity in our dataset, as they both found approximately the same proportion of the 229 TP mutations that were ultimately confirmed, while the sensitivity of JointSNVMix2 was 10% lower (Table 3).
Thyroid nodule investigation was the most common presentation (79%), although two patients were identified following familial RET mutation screening and were ultimately found to have a diagnosis of MTC.
It is these errors in replication, or mutations, that are ultimately responsible for all of the variation that the other three forces of evolution act upon.
Although some number of false positives is inevitable in any candidate mutation set, if the patient cohort is large enough, relevant and actionable mutations will be ultimately identified by their recurrence in multiple patients.
Thus, it is likely that trade-offs resulting from pleiotropy bias the mutations that are ultimately fixed by selection during evolution (Stern and Orgogozo 2009).
They were ultimately acquitted.
The charges were ultimately dismissed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com