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The mutations were then arranged in a family tree.
Combinations of three point mutations were then created via site-directed mutagenesis.
Mutations were then clustered based on corresponding CCF, and subclonal architecture of ctDNA from SCLC was subsequently inferred20.
The constructs with the appropriate PTPRS mutations were then transfected into HCT116 for 48 hours for western blot analysis.
These mutations were then prioritized by other methods of design, mainly the formation of additional hydrogen bonds, an increase in the hydrophilicity of solvent exposed residues, and previously described mutations in other antibodies.
This occurred because targeted genes developed natural mutations that allowed them to continue functioning, and these mutations were then passed down to offspring.
Similar(18)
These mutations are then perpetuated.
The total scores of all false mutations are then 13.0 and 15.0 for NDsq0167 and NDsq0168, respectively.
The instantaneous initiation rate of cells with 3 oncogenic mutations is then proportional to the number of cells with 2 oncogenic mutations, and so on.
A full length product containing the desired mutations was then PCR amplified using JK6, JK7, and the products of the first two reactions as template.
11 20) at the second PCR stage, the five M7b mutations are then mainly located in segments 13, 14, 15, 17, 19, and 20, whereas the two D4 mutations are in segments 11 and 18.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com