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If all mutations were strictly additive or multiplicative in their effects on fitness, then it would be rather easy to describe the structure of fitness landscapes and understand the resulting dynamics of adaptation by natural selection.
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In activated B cells, A∶T mutations are strictly dependent on the Msh2/Msh6 pathway and are presumed to be introduced during patch repair by POLH, in the absence of DNA replication [9], [10].
The changed codon bias indicated that mutations were not strictly neutral [ 101, 110].
Furthermore, carriers of heterozygous NPHS2 mutations should be strictly monitored in the post-graft phase [ 17].
Couples were strictly policed.
Airplanes were strictly off limits.
"Our criteria were strictly sporting".
His responses were strictly elliptical.
Religious issues were strictly forbidden.
The sandwiches were strictly props.
Cars were strictly verboten.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com