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Mutations were quantified using the machine's software.
After PCR amplification of a panel of previously established murine microsatellite markers, frameshift mutations were quantified as NMPM in comparison with tail DNA (figure 4A).
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The perturbation in stability induced by the mutations
Perturbations in amide resonances resulting from the mutation were quantified using chemical shift perturbations (CSPs) calculated as CSP = [(DdH 2+(DdN/5)2]1/2, where DdH and DdN are the observed chemical shift changes for 1H and 15N, respectively.
The chemical shift changes due to this mutation are quantified using eq 3 and shown in Figure 2B for each residue.
The mutation effects were quantified by maximum structural distance (d max ).
PICT1 expression and TP53 mutation status were quantified in 110 cases of primary gastric cancer to explore the impact of PICT1 expression levels on gastric cancer.
Therefore, transition mutation frequencies were quantified for each alignment of TE-like sequences relative to the consensus sequence of the alignment, which served as a model of the intact progenitor element.
The effects of the unc-18 mutations on exocytosis were quantified in C. elegans by measurement of locomotion rate and aldicarb sensitivity.
For this, the number of very rare (or non-dbSNP) Φ mutations in autosomes were quantified in three healthy individuals (two of Arabic and one of European ancestry); and this figure was found to be approximately 60 on average.
A change in a weight is equivalent to a mutation and its effects were quantified as a pleiotropic coefficient, based on the coefficient of variation of the magnitude change at each trait.
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