Sentence examples for mutations were originally from inspiring English sources

The currently accepted hypothesis is that these mutations were originally neutral, meaning that deletion of the vitamin C production pathway had no selective advantage or disadvantage.

Although this pattern cannot be used to determine if the mutations were originally fixed by natural selection, conservation after an ancient diversification indicates a long period of stasis, consistent with purifying selection on adaptive, alternative amino acid states.

Col4a1 and Col4a2 mutations were originally identified because of severe, highly penetrant cataracts and ocular ASD.

These mutations were originally identified and characterised as fly and mouse embryonic lethal mutations that cause early cardiac failure (Schott et al., 1998).

Muscle from transgenic Drosophila larvae was compared with skeletal muscle biopsies from the patients in whom the LMNA mutations were originally identified (Table  1).

KRAS mutations were originally detected in lung cancer (Rodenhuis et al, 1987) and since then have been assessed as a potential marker of survival in colorectal, ovarian and pancreatic cancers.

One of these mutations was originally observed only in a subpopulation of cells.

A sixth and a seventh mutation were originally described in 2011 in individuals stemming from consanguineous Pakistani pedigrees [21].

Transgenic mice expressing a human genomic SOD1 construct with the G93A mutation were originally derived from the Gurney G1 mice, but because of a reduction in the transgene copy number (8 instead of ~20 transgene copy numbers per haploid genome) show a delayed disease onset and are termed G1del mice [ 30- 32].

The dap mutation was originally ascribed to dapC, but feedback reports characterize it as dapA.

The mutation was originally produced by Koller et al. [27] in strain 129.