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Stabilizing nonsense mutations were often found in the regions encoding structural proteins in constructs containing the cDNA of Japanese encephalitis virus (JEV) [11].
Stabilizing spontaneous nonsense mutations were often found in the regions encoding structural proteins in constructs containing the cDNA of Japanese encephalitis virus (JEV) [11].
Past research by Thomashow [39] and further studies by Jurkevitch [40] highlighted a locus, the hit locus, genes Bd0108 Bd0121 where mutations were often, but not compulsorily found in Bdellovibrio strains that were growing as HI.
In general, regions with more non-synonymous mutations were often the subject of selection.
Furthermore, ENU mutations were often directly flanked by G or C nucleotides.
Recent analysis of TCGA RNA-seq data revealed that multiple EGFR deletion and point mutations were often expressed in the same tumor at different allelic frequencies [ 5].
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Stability promotes mutational robustness, as newly introduced mutations are often destabilizing in nature.
Notably, H3.3 is mutated in paediatric glioblastoma and bone tumours, and H3.3 mutations are often associated with changes in global DNA methylation (Salomoni 2013, Maze et al. 2014).
Women with mutations are often advised to have their breasts and ovaries removed as a preventive measure.
Chromosomal mutations are often the starting point of quantum speciation in animals, particularly in groups such as moles and other rodents that live underground or have little mobility.
Random mutations are often harmful.
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