Sentence examples for mutations were lost from inspiring English sources

Most baseline resistance mutations were lost in subject 7 during treatment interruption becoming undetectable even by deep sequencing at the time of virological failure.

Alternatively, perhaps background enhancer mutations were lost, though outcrossed strains were used for the constructions.

Second, the fact that relatively large-effect beneficial mutations were lost in competition supports the finding that beneficial mutations may be much more frequent than believed [ 40, 41].

The likely large costs associated with changes to the EGFR are further exemplified in this study, because after some patients with resistant cancers stopped treatment with TKIs, the resistance mutations were lost, and their tumours once again became sensitive to treatment by either the same or a different EGFR inhibitor.

Of course, many beneficial mutations are lost by random drift while they are rare.

Stochastic selection creates drift, where low frequency mutations are lost despite intrinsically high adaptation scores.

Most early mutations are lost because most stem cell lineages become extinct during crypt clonal evolution.

Somatic evolution is suppressed because only mutations that occur in stem cells are retained, while most other mutations are lost.

This is because all mutations start at a low frequency, and most mutations are lost before reaching substantial allele frequencies.

During this process numerous genetic mutations are lost from the population while mutations which occur concurrently with drug resistance causing mutations (or 'hitchhiking SNPs') remain [ 14].

Since the majority of new neutral mutations are lost by drift, 10,000,000 replicate TE insertions were simulated to ensure that TE insertion alleles were retained in ∼10,000 replicates.