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Exact(14)
The mutated gene was sequenced to confirm that only the desired mutations were inserted.
Site-specific mutations were inserted in primer sequences in order to prevent extension of reciprocally complementary primers.
Matthew B. Frieman, a virologist at the University of Maryland School of Medicine, said that a review of the scientific literature could point to where the mutations were inserted.
The aforesaid mutations were inserted into the strain by using pYX212 vector.
Three pairs of mutations were inserted.
Out-of-frame ATG (uATG) mutations were inserted at −6 bp into the WT, the DPE-L1/2 double mutant and the GLE mutant, transiently transfected into HeLa cells and assayed for CAT activity.
Similar(46)
Finally, when the three mutations are inserted together, the dynamic range of Y195 is more similar to that of wild-type.
Recently a more relevant mouse model was created in which humanized Aβ, with human AD-causing mutations, was inserted into endogenous mouse APP [ 144].
Inherent tendency to diploidization is not an obstacle for screening as long as the mutations are inserted in a haploid state.
The individuals from the youngest generation who had the mutation were inserted into the case dataset.
In this genetic paradigm, the pathogenic human mutation is inserted in the mouse allele.
More suggestions(15)
mutations were introduced
mutants were inserted
mutations were included
mutations were found
mutations were selected
mutations were described
mutations were detected
mutations were eliminated
mutations were verified
mutations were confirmed
mutations were identified
mutations were genotyped
mutations were used
mutations were analyzed
mutations were inherited
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