Sentence examples for mutations were induced from inspiring English sources

The mutations were induced in the modeled structure one at a time using the mutate tool of the Swiss-PdbViewer software and analyses were done based on the "best" rotamer of the new amino acid.

To create biallelic GLIS3 mutant hESC lines, indel mutations were induced in INSGFP/W HES3 cells using an sgRNA targeting exon 3 of GLIS3 gene, predicted to impact all splice variants (Supplementary Fig. 2a and Supplementary Tables 4–6).

In AHR2b, mutations were induced using CRISPR-Cas9 guide RNAs targeting sites in both exon 2 (17%) and exon 3 (63%).

In this study mutations were induced by UV-C radiation.

bulldog mutations were induced and recovered during the large-scale chemical mutagenesis screen carried out in Boston [13].

CXCR4 mutations were induced by site-directed mutagenesis using a QuickChange mutagenesis kit (Stratagene, Heidelberg, Germany).

This study confirms that, when de novo mutations are induced, the induced MF is the same for cultures with normal and artificially high background MFs.

This suggests that the induction of mutations is also associated with genomic instability development during immortality acquirement, although it is still unclear how the mutations are induced.

Such mutations are induced through a similar mechanism as the endogenous mutations, although the absolute extent of accumulation differs among tissues [30].

The stability of an escape mutation combined with the rate at which mutations are induced has important implications for vaccine development.

Since all pools were sequenced in one run, we can assume that mutations are induced by PCR, reverse transcription and T7 polymerase.