Sentence examples for mutations were indeed from inspiring English sources

Acquired drug-resistance mutations were indeed observed in all plasma samples sequenced after failure (data not shown).

To demonstrate that tubulin mutations were indeed responsible for causing the BPR0L075-resistant phenotype, gene transfection and over-expression of the βI-tubulin mutant that contains the above mutations was performed in KB cells.

Immunohistochemical analysis using CD20N antibody revealed that the CD20 molecules with C-terminal mutations were indeed expressed in the lymphoma cells, and located at the cell membrane.

Activity in cells transfected to similar levels (as evidenced by similar mRNA expression) with the three mutant constructs was indistinguishable from mock-transfected controls (Fig. 1A), highlighting that these mutations were indeed inactivating.

Mutations in agmo-1 were predicted to cause cuticle fragility and hypersensitivity, and such mutations were indeed subsequently found in screens for altered resistance to a worm bacterial pathogen that infects animals via the cuticle (Hodgkin et al. 2013).

Whether these mutations are indeed causative and what types of digenic variations may be responsible for LCA needs additional study.

Defenses against unpredictable threats (parasites, fluctuating environment and deleterious mutations) are indeed significantly improved by wider genetic variability and by positive epistasis gained by sexual reproduction.

A number of resistance mutations are indeed termed compensatory or secondary drug resistance mutations since they restore at least partially the enzyme function possibly compromised by the true resistance mutation(s).

To confirm that these mutations are indeed responsible for the synthetic lethality with rps15-1, we crossed the Ins9 and Ins15 strains to either the Δnhp2::kanMX4, rps15-1 or Δutp15::kanMX4, rps15-1 null mutants respectively.

A significantly higher number of G mutations was indeed observed in the WRC or GYW motifs in NBS patients (Fig. 2 and Table 2), whereas G residues outside these motifs were targeted equally (11.3% vs. 11.1% of total mutations in controls).

Such mutations are indeed observed in several types of human cancer including melanoma.