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In all the lines that could grab OmpF, those four mutations were identical, or nearly so.
Since the mutations were identical on both alleles, they may be assumed to be of ancestral origin.
Five of these mutations were identical to the 2 bp insertion we identified in the first HI clone (Figure 3B).
Most mutations were identical in several species, suggesting that a low number of mutations can actually provide resistance.
For the PI 567189 A FAD2-1B allele, two of the missense mutations were identical (S86F and M126V), and the third missense mutation was unique, I143T.
The amino acids encoded by the major allele of 11 of the 16 non-synonymous mutations were identical to the corresponding human RNase L amino acid [UniProtKB: Q05823].
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When the resulted mutations are identical to RNAdistance, they are presented in bold face.
However, while APC/CTNNB1 mutations are identical throughout a clonal tumour, immunohistochemical analysis reveals heterogeneous expression of nuclear β-catenin.
In this case, the visual and selective detection of mutants should reveal the same number of mutants since all mDEL1 mutations are identical.
Some of these mutations are identical to those previously reported to confer sensitivity to some TK inhibitors like erlotinib and gefitinib in non small cell lung cancer (NSCLC) [ 14].
Previous work [ 19- 21] has shown that at equilibrium, when rates of forward and back mutations are identical (u l = u g ), the solution to Equation 1 is a binomial distribution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com