Sentence examples for mutations were estimated from inspiring English sources

The fractions of sites in the coding regions for synonymous, nonsynonymous, and nonsense mutations were estimated to be 28.5%, 68.1%, and 3.4%, respectively.

The A32V and Δ152 164 mutations were estimated to be present in the R6 (pH 5.6) cell population at frequencies of 18.6%, and 11.2%, respectively (Fig. 2A) while 3.3% contained both mutations (Fig. 2A).

59 PALB2 truncating mutations were estimated to be associated with a 2.3-fold increased risk.

Predicted severity of the mutations were estimated in MutPred (mutpred.mutdb.org) [Li et al., 2009].

Odds ratios of carrying gene mutations were estimated by the logistic regression model and are reported with 95% confidence interval (95% CI).

Thirty-five mutations were estimated to be clonal, that is, present in the whole tumor population, either in a heterozygous (n=28) or hemizygous (n=7) configuration.

These pLoF mutations are estimated to knock out 1,317 genes, each in at least one participant.

Time of the mutations was estimated based on the coalescence time of corresponding haplogroups in the mtDNA phylogeny of 36,914 sequences.

In 1997, the lifetime risk of breast cancer in women with BRCA mutations was estimated in the range of 85percentt.

As a result, a woman with one of those mutations is estimated to have a 60%to70%0% chance of developing breast cancer at some point in her life.

Therefore, the lower limit of detection of minor resistance mutations was estimated to be 0.5 3.0% in the previous studies [12], [18], [19], [30], [31].