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Exact(49)
Mutations were considered as "not tolerated" when P<0.05.
Intragenic suppressor mutations were considered separate events, and calculated as such.
Introduced mutations were considered to be detectable if their z-score was higher than all of the significance scores for unexpected mutations (false positives) on the control samples.
Mutations were considered to be somatic only if they were found in an independent tumor-derived PCR product but not in matched normal tissue.
When all mutations were considered, only a significant increase of MTNR1B non-synonymous mutations was observed in ASD compared to controls (MTNR1A ASD: 3.6% vs controls: 4.4% Fisher exact test P = 0.48; MTNR1B ASD: 13.9% vs controls: 10.1%; P = 0.038).
3 possible nucleotide mutations were considered, one of which had a selective advantage compared to the wild type, the other two had the same fitness as the wild type.
Similar(11)
Other mutations are considered to be associated with virulence and clinical severity.
Factor V G1691A (Leiden), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T mutations are considered risk factors for venous thromboembolism.
BARD1 mutations are considered a high cancer risk and need further examination, as their exact function after mutation is relatively unknown.
NRAS mutations are considered important in the genesis of melanoma.
Mutations are considered as sources of species evolution.
More suggestions(15)
mutations were taken into consideration
mutations were hitherto
mutations were found
mutations were identified
mutations was considered
mutations were selected
mutations were described
mutations were detected
mutations were analyzed
mutations were verified
mutations were eliminated
mutations were confirmed
mutations were observed
mutations were made
mutations were created
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