Sentence examples for mutations were conducted from inspiring English sources

Exploratory analyses of the other mutations were conducted to understand the full spectrum of change during treatment: There was no statistically significant increase in any of the other 8 possible mutation types, including all transversions, and, the overall p-value for any effect of treatment on transversion mutations, corrected for multiple testing, was 0.38.

Predictions of changes in protein stability upon point mutations were conducted using CUPSTAT [ 8]. (Auto Phosphorylation sites were predicted using GPS v. 2.1 [ 9].

Mutation detection for germline BRCA1 and BRCA2 mutations was conducted by using direct DNA sequencing and multiple ligation-dependent probe amplification (MLPA), as previously described [ 12, 13].

A search for mutations in exons 2-11 of TP53 mutations was conducted using previously reported primers and methods (Idbaih et al, 2007).

Then, polynomial mutation is conducted on solutions belonging to an individual.

Detection of Ha- ras codon 12 mutation was conducted using a commercial SNP system (ABI, USA) [ 41].

The procedure for mutation was conducted according to the manufacturer's instructions (MutanBEST, TaKaRa Biotechnology) and the mutants were sequenced for verification.

Detection of Ki- ras codon 12 mutation was conducted using a commercial SNP system following the manufacturer's instructions [ 42] (Roche, Germany).

The only other study of breast cancer risk and this polymorphism in noncarriers of a BRCA1 or BRCA2 mutation was conducted in women aged 43 69 years [ 1]; it found no association.

In this context, a multi\e dose-escalating phase I trial to determine the phase II recommended dose of this combination, to determine the impact of oral MC on the IM pharmacokinetic (PK) and to seek some signs of activity in patients with IM and sunitinib-refractory GIST, with chordoma, life-threatening aggressive fibromatosis or melanoma harbouring KIT mutation was conducted.

Bacterial reverse mutation assays were conducted as described previously [ 10].