Sentence examples for mutations were completely from inspiring English sources

Because cyanobacteria have multiple genomes [ 33, 34], PCR was used to determine whether the mutations were completely or incompletely segregated.

It was found that the effects on kpep for all but two of the mutations were completely consistent with their stabilities in the free ternary complex.

Cancer cells carrying BRG1-inactivating mutations were completely resistant to RA-induced CYP26A1 expression, while cells with MYC amplification showed some RA-dependent induction of CYP26A1 (Fig 3F).

We also created the AAA mutation in SRSF1 and SRSF9 and revealed that these mutations were completely non-functional in promoting β-catenin accumulation (Fig 2B D and Supporting Information Fig S2D F).

For both lesions, T → A mutations were completely eliminated in the pol V-deficient strain, even though it remained approximately the same in pol II- and pol IV-deficient strains relative to the wild type.

Many disease-causing mutations were completely unsuspected on the basis of previous knowledge (Altshuler et al., 2008), and software tools that aim at predicting the damaging effect of non-synonymous variants (Adzhubei et al., 2010; Kumar et al., 2009; Schwarz et al., 2010; Sunyaev et al., 2001) are currently unable to reliably distinguish between disease-causing mutations and other variants.

Most of these mutations are completely penetrant, although the recently described Glu318Gly substitution seems to have only partial penetrance.

Therefore, our results do not imply that clustered mutations are completely indistinguishable from non-clustered mutations.

Thus, the presence of disruptive TP53 mutations was completely unexpected.

Normally, assuming that mutations are completely random, the Ts/Tv would be 0.5.

At the balance, new a alleles generated by mutations are completely removed by selection.