Suggestions(2)
Exact(4)
The rates of KRAS mutations were comparable in CIMP-high (35.3%) and CIMP-low/negative carcinomas (34.1%).
The specificity and sensitivity of the other four methods for protein-truncating mutations were comparable to those of full sequencing ('gold standard').
However, despite these differences in the Ras protein (H-RasQ61L or K-RasG12D) and the levels of expression of the mutant, the cooperation of the either K-Ras or H-Ras mutations were comparable.
Mature KI/KO males with the three different Tex11 KI alleles (three point mutations) were comparable to KI/KO males with a wild-type Tex11 KI allele (hereafter referred to as wild-type KI/KO) in respect to body weight, testis weight, and fecundity (Fig 6B, C and E).
Similar(56)
When tested for complementation or multicopy suppression of the defective Sso1p or Sso2p, the functionality of mutant proteins containing all mutations was comparable to that of the wt proteins in vivo (Figure 2A, Table 1).
Their methods to analyse germline mutations are comparable with those used in our study.
The occurrence of various types of mutations is comparable to other studies of this size [ 21, 24, 26, 27], but some differences are also apparent.
This is consistent with recent data that indicated that the respective frequencies of BRCA1 and BRCA2 mutations are comparable in early onset breast cancer.
These results reveal that the frequency of EMS-induced transition and transversion mutations is comparable between different individual mutants that were derived from the same mutagenized population.
The ΔΔ GU values for [R16nva] mutations are comparable to, or significantly larger, than those due to acidification (see Table 1).
This suggests that the dependence of fitness on free energy is described by a smooth landscape in which the deleterious effects of many non-epitope mutations are comparable in magnitude to the beneficial effects of epitope changes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com