Sentence examples for mutations were chosen from inspiring English sources

The mutations were chosen according to mutational work on mammalian ionotrophic glutamate receptors, which resemble the binding domain of QBP in structure and sequence [25].

The mutations were chosen to improve 2-ethyhexanoic acid production by decreasing active site volume, increasing active site hydrophobicity, and improving stereoselectivity.

Six independently isolated suppressor mutations were chosen for characterization and sequencing.

Sequences of scanning mutations were chosen to preserve the GC composition of the sequence but to avoid introducing known regulatory elements.

For this study, seventeen primary HIV-1 drug resistance-associated mutations were chosen based on definitive phenotypic resistance profiles in HIV-1 subtype B infections [11] (hivdb.stanford.edu, accessed in April 2008; Figure 2A).

These three mutations were chosen because of their different effects on the activity and conformational stability of HMBS.

Potentially attenuating mutations are chosen based on available knowledge of the molecular biology of the virus.

A minimum of three unique mutations was chosen to ensure that potential base mis-incorporation artifacts were excluded.

Two sequences having at least one base mutation were chosen from families with sequences greater than 20 (Table 1).

HCT116, a colon cancer line that harbors a KRASG13D mutation and IPC298, a cutaneous melanoma cell line bearing an NRASQ61L mutation, were chosen for this study since KRAS in colorectal cancer and NRAS in melanoma is the most frequently mutated RAS gene in these tumor types.

To simulate heterozygous carriers, input reads covering the mutation were chosen at random for sequence manipulation with an average probability of 0.5.