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For example, two unique mutations were captured from the isolates of Thailand in 2006.
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In this case, Equation (2) can be rearranged into a differential equation where mutations are captured by the mean mutational effect and the mutational variance (Tsimring et al., 1996; Cohen et al., 2005; Neher and Hallatschek, 2013).
It is surprising that no additional passenger mutations are captured between the occurrence of the initiating event (chromosome 2 deletion) and the second hit (R235 point mutation), as the latency for murine rAML is over a year.
While the cumulative effect of these mutations is captured in the model, with a single mutant haplotype predicted to establish at generation 91 (inferred fitness 0.12), no distinction between the two haplotypes can be made, leading to a clear discrepancy in the haplotype plot (Fig. 2g).
In the Holstein population analysed in our work, the effect of this mutation is captured by two SNP, one very close to the gene, and one ~200 kb away.
Given that most of the increased tumorigenic efficiency due to a mutator mutation can be captured by the case in which the mutator mutation is an initial step [15], we focus in the mutator pathway analysis for case 1 on mutator mutations occurring as an initial step.
Three were captured.
Both were captured in early 2003.
They were captured and returned.
Several others were captured.
Nearly 3,000 were captured.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com