Sentence examples for mutations were acquired from inspiring English sources

The fact that the MDR and XDR strains have different mutations in rpoB and pncA suggests that they arose separately, and that these mutations were acquired independently after divergence.

This finding suggests that these mutations were acquired before dissemination.

These mutations were acquired during PanIN progression culminating in formation of the parental clone.

This suggests that these 81 frameshift mutations were acquired before the divergence of strain 210 from these other strains.

Each of these alleles arose directly from the ancestor, but became more dominant when additional mutations were acquired.

All 81 of these genes also contained a frameshift in M. africanum, which suggests that these mutations were acquired before the divergence of the M. tuberculosis complex.

The question has been posed regarding how might the requisite genetic changes, estimated to be about six mutations, be acquired to initiate oncogenesis, and whether mutator phenotypes participate in the process [ 56].

Tumors may become dormant, or even regress, but growth can start up again if new driver mutations are acquired.

Simulations predict that the specific order in which mutations are acquired is crucial for determining the pace of cancer development.

If enough deleterious passengers accumulate, tumors may become dormant or even shrink, but growth can start up again if new driver mutations are acquired.

Now, to add even more nuance, new research suggests that the order in which the mutations are acquired is important in determining how the disease will develop.