Sentence examples for mutations we studied from inspiring English sources

Even though the MCR4 mutations we studied are relatively rare (∼5% of severe obesity), the obesity phenotype allowed them to be identified and rapidly tested for the biochemical consequences of the mutation.

The molecular pathogeneses of these three candidate genes mutations we studied here are different.

To further characterize the mutation frequency and phenotypes associated with tubulin mutations, we studied a cohort of 60 foetal cases.

In fact, although we were manipulating the largest scaffolding subunit of the proteasome, only a small number of the mutations we studied had any negative consequences on proteasome stability.

Cit++ cells must balance using both glucose and citrate, so the optimal level of CS activity in these cells is predicted to be low but not zero, consistent with the effects of the gltA2 mutations we studied.

In order to evaluate if this gain of regulatory activity in colon tumor cells may be related to somatic mutations we studied the degree distribution (as indicator of regulatory activity) for TFs and target genes, classified as frequently mutated (if present in COSMIC database) or not [ 10].

However, although the mutations we study are unlikely fodder for evolution, the genes they identify might, if their functions were more subtly altered, tweak behavior in adaptive ways.

Later, taking full consideration of back mutations, we study the effect of lethality on the error-threshold by examining the equilibrium population distribution and the ancestor distribution in the genotype space as a function of error rate.

Second, with the full consideration of back mutations, we study the equilibrium population distribution and the ancestor distribution in the genotype space as a function of error rate with and without lethality in a multiplicative fitness landscape.

In order to study the biochemical consequences of this mutation we studied reactive oxygen production and enzymatic activity of respiratory complex (RC) IV (cytochrome oxidoreductase).

To learn about the time and location of origin of the A111T mutation, we studied haplotypes in the region around SLC24A5 across world populations.