Sentence examples for mutations we isolated from inspiring English sources

In the set of the evolutionarily conserved mutations, we isolated the P1 mutant, in which a conserved tyrosine residue is mutated to a histidine residue.

Of all the GOF mutations we isolated, W275S stood out.

Table 2 displays a list of the new mutations we isolated as suppressors of the vps20Δ, vps32Δ or vps3Δ alleles.

Because Mth1 and Rgt1 work together to repress genes involved in growth on poor carbon sources, we expect that the mutations we isolated are loss of function mutations.

To determine the molecular consequences of the mtp5-1 mutation, we isolated RNA from mtp5-1 plands and reverse-transcribed and PCR-amplified the mtp5-1 locus.

To ascertain if the epitope tag on the ribosome subunit was exacerbating the effect of the cdc48-3 mutation, we isolated ribosomes from untagged cells by pelleting through a sucrose cushion (Halbeisen and Gerber, 2009).

Since strong loss-of-function alleles of lin-12, apx-1 and sel-12 cause lethality, dramatic vulval morphogenesis or general muscle morphology phenotypes, which are all absent in lin-12 wy750) lin-12 wy750ls, it is likely that the mutantse mutanimalse itolated represents a partislikely-of-functhat allele.

To measure the fitness effect of sterile mutations alone, we isolated spontaneous steriles derived from the ancestral strains and measured their fitness under the experimental conditions (sste, gray bars in Figure 5B).

ot266 is a recessive mutation that we isolated in a screen for mutants with defective dopaminergic neuron specification ("Dopy:" phenotype), as assessed by expression of the dopaminergic marker dat-1 gfp dat-1 gfp from thexpressedne vtIs1)[13].

To identify the genetic basis of the EMS mutation in ehy5, we isolated the new ehy5 mutant, from the hy5KS50 ehy5 double mutant background.

We have identified and characterized also a novel TRKB point mutation, TRKBP507L, which we isolated from the MDA-MB-435 tumor cell line.