Sentence examples for mutations we introduced from inspiring English sources

Moreover, it seems highly unlikely that the point mutations we introduced in the Syt1/7 chimera, or replacement of the linker region, might cause folding problems because all these mutated residues are surface exposed.

To confirm the increase in antigen recognition capability by the amino acid mutations, we introduced the mutations observed in clone11 into the KM10 scFv gene.

In order to analyze the phenotypes induced by the D33N and C77W mutations, we introduced the individual mutations into yeast RPS26A.

To genetically complement the insertion mutations, we introduced a genomic ARR22 DNA fragment into the arr22-2 and arr22-3 mutant lines.

In order to recapitulate the biological role of the original crizotinib-resistant mutations, we introduced them in the fusion protein where they were detected for the first time.

The mutations we introduced to the second palindrome also resulted in a complete loss of silencing by XIST, supporting the importance of these sequences; however, these mutations did not directly address secondary structure formation.

To obtain a high supply rate of beneficial mutations, we introduce positive selection at high frequency, specifically at one site in every τ=1000 generations, which is faster than the rate of establishment.

We tested whether the mutation we introduced (E457Q) would change hSGLT3 sugar K0.5s to render them similar to hSGLT1.

For the second mutation, we introduced a premature stop codon that truncated the BRCA1 protein by deleting the last 10 C-terminal amino acids.

To ask whether the presence of the serine at position 62 was responsible for the large impact of the T63S mutation, we introduced a S→T change at residue 62 to make a Kcv sequence, Kcv TT), that resembles the Kir2.1 filter sequence.

To test whether the R23E mutant effect could be neutralized by a second mutation, we introduced the inhibitory T49E mutation into the R23E variant.