Sentence examples for mutations we extracted from inspiring English sources

Second, with the remaining mutations, we extracted the features which have discriminative power between LoF and GoF mutations.

To assess the somatic status of the mutations, we extracted DNA from manually isolated peritumoral tissue fragments (only available for 8 samples).

To test the samples for KRAS exon 2 mutations, we extracted the DNA from the tumour samples and determined the sequence in codons 12 and 13 by pyrosequencing.

Because the methods described in the previous section do not require outgroup sequences or polarization of the direction of mutations, we extracted within-species polymorphism data for the four plant species separately.

To further understand the interaction between treatment, host genetics and tumor-specific mutations, we extracted DNA from four sources obtained from a single patient carrying a deleterious mutation in BRCA1 (blood, primary tumor, omental metastasis and relapse (recurrence) following standard post-operative therapy with carboplatin and paclitaxel).

For each potential point mutation, we extracted those with coverage reads more than 10 and a ratio of variant read to wild-type read more than 0.6.

Next, we extracted mutation subtypes from the LoF and GoF mutations and compared their distributions.

Further, we extracted 3,173 mutations in 2,695 residues belonging to 5,820 fragments (422 fragments from homogeneous clusters and the remaining 5,398 from heterogeneous clusters) from over 9,000 abstracts.

We extracted 26,404 mutations (3,419 proteins) with disease annotations but no annotated functional effect.

We extracted 3,329 mutations with listed stability changes and cross-checked all the sources where the measurements came from.

(4) Set of mutations with unknown disease relation : We extracted 251,414 variants (28,913 proteins) without known disease associations.