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When constructing NJ trees using synonymous mutations, we did not observe species specific topology in the phylogenetic trees of exons 2 and 3 (data not shown).
When comparing individually CHD1 deletions, MAP3K7 deletions, and SPOP mutations, we did not observe significant differences in genomic burden for any one lesion.
In this set of de novo synonymous mutations, we did not observe any significant codon usage shift [P SH ≤ SH_r) = 0.485].
However, in our entire set of predicted splicing mutations, we did not find any pertaining to the intron between exons 12 and 13.
For de novo synonymous mutations, we did not find any significant codon usage shift [P SH ≤ SH_r) = 0.868 for 27 mutations in 27 genes, SH = −6.12].
As for EGFR mutations, we did not observe discordant results between primitive and metastatic tumors for KRAS mutations, indicating that they are generally acquired prior to metastatic spread, but our matched series and studies on this subject are still too few to draw firm conclusions (Table 3).
Similar(53)
Despite the functionality of the -151C/T GHSR mutation we did not find a significant impact of this mutation in the general population of adult Danes.
Other than the de novo POGZ mutation, we did not identify additional molecular events that would account for her phenotype.
In the two patients carrying a BRAF mutation we did not detect any point mutation in the K-Ras gene (Table 2).
When we introduced a single copy of a chromosome carrying the Caf1p55 short mutation, we did not observe any discernible effect on the GMR-Gal4;f00391 rough eye phenotype.
Although we hypothesized that neck ventroflexion in cats could be associated with a thyrotoxic or familial periodic paralysis channel mutation, we did not identify any previously detected human channel mutation in the hyperthyroid cat presenting hypokalemia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com