Sentence examples for mutations we detected from inspiring English sources

In this study, we aimed to elucidate whether Bcl11b is mutated in lymphomas with allelic loss, and whether the mutations we detected conferred any effect on cell proliferation and apoptosis.

However, one of the mutations we detected, R304W, appeared to be associated with a high risk of breast cancer.

Of 31 clinically relevant disease mutations, we detected all 31, for a sensitivity at disease-causing loci of 100%9595% CI: 88.8 100%).

The individual vma3, vma11, and zhf mutations we detected are therefore necessary and sufficient for conferring resistance to indolotryptoline-based compounds.

The promoter and attenuator mutations we detected were very remarkably similar to those that had been previously described in France, South Africa, Sweden, and Toronto, Canada.

The 4 new types of nonsynonymous, and 5 of synonymous, mutations we detected among 539 samples analyzed provide clues to understanding artemisinin-resistant parasites.

In genes with detectable cis-regulatory variation, derived alleles show a skew similar to non-synonymous changes, suggesting that the regulatory mutations we detect may be associated with fitness costs commensurate with non-synonymous mutations.

These results further pinpoint the mutation we detected at the hit locus as the single mutation associated with the HI phenotype in the HI mutant sequenced by NGS.

The frequency of p16 mutation we detected is higher than previously reported in EA or in BE found in surgical resections [11], [15], [30], [50] [53].

Besides the G12V HRAS mutation used in the transformation experiment to derive the premalignant cell line MCF10AT from MCF10A, the only mutation we detected was PIK3CA H1047R, which is known to be the most common activating mutation in the PIK3CA gene in human cancer [15], [16].

Eight strains contain the same zhf1 mutation (W324L) observed previously, making it the most common mutation we detected.