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Exact(4)
A significantly higher proportion of PIK3CA mutations was seen in Ta cases compared to T1 (p<0.05, Chi-2 test), but not between T1 and ≥T2, or between NMI and MI cases.
A 2 log advantage for the strain incorporating the three mutations was seen after irradiation at 2000 Gy.
The highest frequency of K-ras mutations was seen in large adenomas of the villous type with high-grade dysplasia.
A higher incidence of B-Raf mutations was seen in patients with low-grade neoplasms, primary tumor location outside the sigmoid colon, and neoplasms other than tubular.
Similar(56)
Although infrequently mutated in spontaneous tumours, LKB1 point mutations were seen in a pattern mirroring those seen in association with PJS, including cervix, gastrointestinal, and pancreas (Avizienyte et al, 1999; Sanchez-Cespedes, 2007).
There was no difference in frequency between low and high grade tumors and TSC1 mutations were seen in FGFR3, PIK3CA, and in TP53 mutated cases.
Non-p.V600E codon 600 mutations were seen in 8 of 68 (12%%) BRAF-mutated melanomas.
GWAS mutations are seen because, though puny, they are common.
BRAF mutations are seen in about 10%% of mucosal melanomas.
CTNNB1 mutations were seen in 3 cases (2%).
Nineteen EGFR mutations were seen in cases with no gain on 7p.
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