Sentence examples for mutations was limited from inspiring English sources

At the time the study was designed, knowledge regarding additional risks to men due to BRCA1/2 mutations was limited; therefore, it was not deemed appropriate to ask men about their risk of developing cancer.

Before the development of this technology, analysis of tumor formation in mice with inactivating mutations was limited to mice heterozygous for the specific mutation [74] or chimeric mice partially derived from embryonic stem cells homozygous for a particular mutation [75].

For instance, the researchers have found the altered proteins only in brain cells that control motor functions; they cannot explain why the mutations are limited to these cells.

Studies assessing the impact of other molecular alterations rather than KRAS mutations are limited.

All proteolytically inactive mutations were limited to the globular Domain 1, providing evidence that this part of the passenger domain solely encodes the proteolytic activity.

While the characterization of the effects of most αB-crystallin mutations is limited, the effects of the R120G mutation on protein structure and chaperone activity have been extensively investigated [27] [30].

Thus, histopathological estimates of tumor-cell content are not predictive of the frequency of mutant alleles, while the ability to detect mutations is limited by the allele frequency but not by the tumor cell content.

Although, it should be noted that samples with mutations are limited.

The predictive power of the Koel mutations is limited and improvement restricted to a few years.

Nonsurgical options for breast cancer risk reduction in women with BRCA1/ BRCA2 mutations are limited.

Every category of mutation was represented among VWS families, whereas PPS mutations were limited to missense, nonsense, and splicing mutations.