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The potential effect of the N263D and N260D mutations was evaluated by homology modelling of the mutated sequences using the 3D structure of bovine complex III stored in PDB (1NTM) as a template.
Using the same mutational strategy, mutations were introduced into the ERev protein and the effect of mutations was evaluated in a Rev nuclear export activity assay (Fig 4A).
The impact of tissue necrosis on the cobas EGFR test detection of mutations was evaluated.
The randomness of nonsynonymous mutations was evaluated by the runs.test function [ 67] in R [ 68].
The effect of the mutations was evaluated in silico, using PolyPhen software v2.0.23 http://genetics.bwh.harvard.edu/pph2/.edu/pph2/
In adenoid cystic carcinomas, the impact of the identified UTX missense mutations was evaluated by introduction of these UTX mutants in HEK293T cells, which led to an increase in cell growth and a decrease in H3K27me3 levels.
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Five different mutations were evaluated, in these both splice donor sites were mutated from GT to (i) CT (pHIV-1SDm2SE); (ii) GA (pHIV-1SDm2.1SE); (iii) GG (pHIV-1SDm2.2SE); (iv) AT (pHIV-1SDm2.3SE) or (v) GC (pHIV-1SDm2.4SE).
An extensive series of deletion and site-directed mutations were evaluated for their ability to rescue the myoblast fusion defects of sns mutant embryos.
WNT7A gene mutations were evaluated as a potential cause for Müllerian duct derivative abnormalities in human females.
Additional mutations were evaluated by MAGE combined with amplicon sequencing, revealing role of rho, lrp, pykF, eno, and rpoB on tolerance and fitness in minimal medium.
Maternal risk factors for the emergence of nevirapine-resistance mutations were evaluated.
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adjustments was evaluated
times was evaluated
variations was evaluated
transfer was evaluated
mutant was evaluated
mutations was detected
mutations was confirmed
mutations were evaluated
mutations was coupled
mutations was determined
mutations was followed
mutations was carried
mutations was observed
mutations was introduced
mutations was calculated
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