Sentence examples for mutations was estimated from inspiring English sources

Time of the mutations was estimated based on the coalescence time of corresponding haplogroups in the mtDNA phylogeny of 36,914 sequences.

In 1997, the lifetime risk of breast cancer in women with BRCA mutations was estimated in the range of 85percentt.

Therefore, the lower limit of detection of minor resistance mutations was estimated to be 0.5 3.0% in the previous studies [12], [18], [19], [30], [31].

Overall, the sensitivity of the microarray was estimated to be 73.3%, while the sensitivity of the microarray with respect to missense mutations was estimated to be 95.65% (22/23 detected; Table 2).

The mutation frequency for BRCA2 mutations was estimated to be 0.068% (95% CI: 0.033 0.141%).

The frequency of SHANK3 mutations was estimated to 0.5 1% in AD individuals.

These pLoF mutations are estimated to knock out 1,317 genes, each in at least one participant.

As a result, a woman with one of those mutations is estimated to have a 60%to70%0% chance of developing breast cancer at some point in her life.

The fractions of sites in the coding regions for synonymous, nonsynonymous, and nonsense mutations were estimated to be 28.5%, 68.1%, and 3.4%, respectively.

In women with early-onset breast carcinoma unselected for family history, the prevalence of BRCA1 mutations is estimated to be between four and nine percent [16] [23].

The A32V and Δ152 164 mutations were estimated to be present in the R6 (pH 5.6) cell population at frequencies of 18.6%, and 11.2%, respectively (Fig. 2A) while 3.3% contained both mutations (Fig. 2A).