Sentence examples for mutations utilizing the from inspiring English sources

A portion of the RS2 gene [GenBank: EU651888] was screened for mutations utilizing the TILLING strategy [ 4]; four lines were identified which contained single nucleotide polymorphisms (SNPs).

Several commercial assay kits, such as the Ipsogen MutaScreen, have been introduced for the sensitive semiquantification of JAK2 V617F and common MPL mutations utilizing the minor grove binder (MGB) probe.

Testing the probability of shared polymorphisms arising via gene conversion vs. independent mutation utilized the approximation of the hypergeometric distribution (implemented in DNASP; method described in [ 26]).

The targeted introduction of mutations utilizing sequence specific transcription activator-like effector nucleases (TALENs) and the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) 9 system (RNA-guided nucleases, RGNs) has revolutionized reverse genetic approaches in numerous model organisms.

All sequences were screened for drug resistance mutations (DRM) utilizing the Calibrated Population Resistance tool (Gifford et al., 2009), and then evaluated in the context of the transmission cluster in which that individual was a member.

In this study, we present a highly customizable method for quantifying copy number and point mutations utilizing a single-color, droplet digital PCR platform.

Note that while most of the mutations utilized here have been described in multiple VHL families, a few of the mutations (used here and in other reports) are not especially common and have been classified based on a single family.

To compare the effect of APP K16N with other FAD mutations we utilized the arctic mutation E22G which is located close to the α-secretase cleavage site.

Since the majority of the type 1 VHL mutations utilized so far in our assays were major alterations in pVHL, additional type 1 VHL mutations, all missense (S65W, N78S, and L158P), were studied.

We have sequenced the promoter, exons, and splice junctions of FMR1 in 51 unrelated patients with several classic features of FXS but without the full mutation utilizing resequencing arrays.

K-ras mutations were identified by utilizing the polymerase chain reaction (PCR) technique to amplify the second and third exons (GenBank accession NC_00072, the start codon of K-ras is located in the second exon) followed by sequence analysis of the amplified product.