Sentence examples for mutations under a from inspiring English sources

Besides, viruses with robust polymerase complexes might be more capable of creating adaptive mutations under a selection pressure.

Viruses with this specific PB2-PB1 combination were also found to be more capable to generate adaptive mutations under a new selection pressure.

Under a very low beneficial mutation rate, where competition between clones is rare, mutations under a range of strengths of positive selection would be likely to fix.

These novel and powerful experimental techniques can be utilized to determine fitness distributions of growth rate changes conferred by specific mutations under a variety of environmental conditions.

Simulated data are obtained by adding mutations under a stepwise mutation model [ 56] for short tandem repeats (STRs) and an infinite sites model [ 57] for sequence data.

The lethal fraction (L) of those mutations under a Poisson model is found as e−4.6 L = 0.05, or L = 0.65.

The disease has been replicated by generating a mouse line expressing hAPP751 with the E693Q mutation under a murine Thy1.2 promoter.

Next, we simulated mutation under a SMM (see Materials and Methods) starting from a most parsimonious ancestral DYS385a,b allele combination for each haplogroup that was equivalent to the modal combination, and considering the mean value and the upper and lower 95% confidence limits of the TMRCA, to give three simulated distributions of allele combinations (and δr values) in each case.

In summary, we describe here a novel genetically engineered mouse model of invasive PCA driven by MAPK activation via inducible BRAF mutation under an androgen-insensitive promoter.

DOI: http://dx.doi.org/10.7554/eLife.07236.008 We next generated stable Drosophila transgenic lines that express full length Ana2-GFP containing the CCCD-A mutations under the control of the ubiquitin promoter (Ana2-CCA-GFP).

The final scoring system, a measure of confidence that the point mutations under consideration will define a viable or non-viable virus, is a combination of scores that are based on both identified sequence and structure features.