Sentence examples for mutations to such from inspiring English sources

In some proteins, mutations to such residues can radically change the primary folding route.

Functional studies are required to further elucidate the mechanism of PrP deposition in the myelin sheath, and the propensity of N-terminal mutations to form such inclusions.

The concept can be generalized beyond somatic mutations to other modalities such copy number, methylation, and microarray data.

Further studies, with a more detailed patient history, may help correlate mitochondrial mutations to disease factors such as age of onset and response to treatment.

For instance, it is possible that neural stem cells pass on mutations to downstream progeny such as oligodendrocyte precursor cells (OPCs), which are putative glioma cells of origin.

Moreover, mutations causing resistance to such insecticides would probably seriously affect fertility and individuals carrying the mutations would be quickly eliminated from the population.

Later modelling work that did include sex-specific host modifications and focused on the special case of complete elimination of CI found such mutations to spread easily [22].

This allows such mutations to accumulate at the population level and to be maintained at a low frequency.

We have already published a study of the effects of such mutations to nonpolar residues in α-helices.

Conversely, most protein truncating BRCA1/2 mutations are presumed to be pathogenic, thereby permitting women harboring such mutations to be provided appropriate clinical counseling and management.

Although it is challenging, if we obtain mutations that enhances the expression of transgenes generally, we will be able to apply such mutations to increase the expression of useful genetic tools.