Sentence examples for mutations to specific from inspiring English sources

But in many cases, scientists would like to better direct these mutations to specific regions of the genome and make changes to several sites at the same time.

Though it is assumed that mutations in these vesicular trafficking factors promote tissue growth in part by removing developmental blocks to excess cell division, there is little direct evidence that links ept, vps25, or syx7/avl mutations to specific cell cycle transitions or to core components of the nuclear cell cycle machinery.

Several mechanisms can inhibit oxygen consumption, such as changes of mtDNA and mutations to specific nuclear genes.

It is clear now that a variety of mechanisms exist for directing mutations to specific targets that are relevant for adaptation under the given conditions.

For the stop codons this should be not very difficult to trace to these mutations to specific branches of the evolutionary tree.

Mapping the mutations to specific domains had the advantage of adding the critical functional context necessary for explaining how the mutations potentially contribute to disease.

Thus, at present, it is difficult to assign the COO– signals affected by the D2-K317R mutotion to specific carboxylate residues.

First, mapping a newly induced mutation to specific chromosomes is inexpensive and routinely conducted, regardless of the type of follow-on sequencing performed.

However, a recent study modelled patient mutations onto POLG crystal structure and noted that in 3D, the mutations fall into specific functional domains, and specific combinations of mutations led to specific phenotypes (Euro et al., 2011).

Alleles with mutations targeted to specific sites were constructed by assembling individual PCR products without need for recombinant DNA plasmid cloning.

RCDP type 5 results from a genetic mutation leading to specific loss of only the Pex5 long isoform (Pex5L).