Sentence examples for mutations to predicting from inspiring English sources

From identifying IDH1 mutations to predicting radiation response, mathematical modeling has already demonstrated a potential for clinical effectiveness.

Furthermore, Drugscore-PPI was used for computational alanine-scanning of a dataset of 18 targets with a total of 309 mutations to predict changes in the binding free energy upon mutations in the interface.

In contrast, others reported TP53 mutations to predict sensitivity to a dose-dense epirubicin-cyclophosphamide regimen [16].

These findings emphasize the importance of investigating PRNP polymorphisms or mutations to predict disease occurrence.

Recently, Hofree et al. reported a network-based stratification approach that can use somatic mutations to predict cancer subtypes [ 15].

Similar to what has been recorded by others [4], we found TP53 mutations not to predict resistance to paclitaxel treatment.

These studies clearly suggest that PI3KCA mutations seem to predict cell response to rapalogs.

In silico mutation evaluation to predict protein structure, was conducted using two programmes: Mutation taster [8] and PolyPhen-2 [9].

Within the prioritized variants, those harboring truncating mutations or mutations predicted to be damaging were considered to be the most promising candidates.

These include splice site variants, frame-shift mutations, nonsense mutations and missense mutations predicted to be disruptive.

For example, in most cases, the influence of a novel fetal mutation is hard to predict.