Sentence examples for mutations to determine from inspiring English sources
The silent (synonymous nucleotide variant) and non-silent mutation status for all other genes was then determined separately on a sample by sample basis and compared to those samples with non-silent mutations to determine the number of times the gene is mutated in a tumor with or without the mutated proto-oncogene.
The obvious extension of this work then is to screen wild populations of sheep for these mutations to determine if they are present and if the frequencies match expectations.
Over many years we and others have used these mutations to determine the effects of checkpoint proteins in responding to telomere uncapping [13,39,40,45].
This histogram can then simply be compared to observed number of mutations to determine how likely it is that they are real.
We investigated cells from Lynch syndrome patients with splice site mutations to determine whether splicing aberrations were associated with altered nucleosome positioning at exon-intron boundaries.
RFLP was also used to screen the families of probands with potential mutations to determine segregation of the variant with the FH phenotype (Supplementary Table 2).
The GA method uses genetic operands (crossover and mutation) to determine the best ECVs from a set of initial and new crossover ECVs.
The new study used the genetic information to arrange the branches on the family tree of placental mammals but didn't use a molecular clock inferred from rates of mutation to determine when the various branches first appeared, Yoder says.
We carried out a similar experiment with the trxB promoter carrying either the G-44A or G-33A mutation to determine which residue is critical for Spx binding; however, the trxB promoter carrying the single mutation did not show a significant difference from the wild-type promoter in EMSA analysis (data not shown).
A male fetus is tested by direct analysis for a known familial mutation to determine if he is affected.
We used RNAi and a mutation to determine whether decreased function of cisd2 (the fly orthologue of CISD2) led to obvious phenotypes in Drosophila.
