Sentence examples for mutations to both from inspiring English sources

Our data additionally confirm responsiveness of cells with FOP ACVR1 mutations to both BMP and Activin A ligands.

Therefore, vectors which contained mutations to both the major and minor splice donor sites were constructed.

Six viruses with resistance mutations to both 3TC and NVP had additional resistance to d4T and/or AZT.

At baseline, 429 of 446 (96%) participants had resistance mutations to both NNRTI and NRTI drugs (Table 1).

The contribution of BRCA1 mutations to both hereditary and sporadic breast and ovarian cancer (HBOC) has not yet been thoroughly investigated in MENA.

The mutations to both sides of the recombination point are then exchanged between the two chromosomes, forming the recombinant genotypes A1 B2 and A2 B1.

The bacterium P. fluorescens SBW25 can evolve resistance by de novo mutation to both the antibiotic kanamycin and the phage SBW25Φ2.

Clones were selected that showed frameshift mutation to both endogenous Jarid2 alleles, and western blots confirmed the absence of detectable Jarid2 proteins.

If GluN2B-mediated signaling, specifically in principal cortical neurons, is directly involved in regulating levels of despair-like behavior in response to NMDAR antagonism we would expect the 2BΔCtx genetic mutation to both mimic and occlude the actions of ketamine.

As a control, we also made two point mutations to Id2, both of them outside of the canonical HLH motif: V86K is four amino acids C-terminal to the HLH motif, while L124K is 42 amino acids away.

To address whether m6A residues modulate IAV RNA function in cis, we mapped m6A residues on the IAV plus (mRNA) and minus (vRNA) strands and used synonymous mutations to ablate m6A on both strands of the hemagglutinin (HA) segment.