Sentence examples for mutations to basic from inspiring English sources

We also introduced charge-reversal mutations to basic residues in the ZFD.

(D) Methyltransferase activities for the METTL3-METTL14 harboringers harboring point mutations to the basic residues.

For each residue, a 20-dimensional vector was calculated to denote the conservation probabilities of mutations to 20 basic amino acids.

Single proline mutation and acidic to basic mutation of different interacting residues followed by individual GOLD runs explored the importance of Ser520 and Asp522.

However, there is no proven technology that allows the generation of targeted mtDNA mutations to study the basic characteristics of mitochondrial biogenesis.

Thus, organisms with mutations to genes directly involved in basic genome structure, maintenance and replicative fidelity would understandably have an accelerated aging phenotype and/or shortened life spans.

P4 is generally considered to be critical for furin cleavage, but we found limited variation in this residue position for the FIPVs tested and found mutation to the polar basic residue (K) or polar uncharged residue (S) in <5% of viruses.

In this review we discuss the clinical and genetic basis of cystic fibrosis, the development of treatments targeted at specific classes of CFTR mutation to address the basic defects and improve CFTR function, and the advent of precision medicine in cystic fibrosis as a paradigm for other respiratory diseases.

For example, (i) comparison to other MeCP2 mutations close to the basic cluster would be useful (ii) proof that DNA binding of the full length MeCP2-R306C is also impaired.

In order to reveal how desmin mutations influence basic filament assembly properties, a consecutive study investigated their assembly properties at the protein level [ 12].

We chose to pursue two particularly interesting RTT-causing mutations within the basic cluster: arginine to histidine at residue 306 (R306H) and lysine to glutamic acid at residue 304 (K304E).