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As mutagenized strains contain a significant mutational load, it is often still necessary to map mutations to a chromosomal interval to elucidate which of the WGS-identified sequence variants is the phenotype-causing one.
A. M. Homes on writing novels, and on growing up in Washington, D.C. "All the markers of Wolfe's stylistic DNA were adaptive mutations to a competitive climate, search — engine optimization for the typewriter age".
Of course since pseudogenes generally sustain arbitrary mutations to a higher degree than do functioning genes, we should not expect these correlations to be without exceptions.
Therefore, by making an appropriate series of small mutations to a machine code program, one can generate a program with good performance for any particular simple task [18].
Finally, addition of a subset of the above non-attenuating, adaptation mutations to a DEN2/4 chimeric vaccine candidate was found to increase the virus yield in Vero cells by up to 500-fold.
Random mutations in a man's sperm pile up as time goes on, and passing on more genetic mutations to a child can increase his or her odds of developing autism, schizophrenia and other diseases, according to a recent study published in the journal Nature.
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Using our observations on specific packing, we suggest mutations to an engineered HIV RNase-H to make its function better.
We tested the correlation between individual drugs and individual mutations to an indicator of agreement/disagreement of the three engines.
Of 48 cancer implicated genes evaluated, only VHL, PTEN, and TP53 showed mutations to an apparent extent.
It is, rather, the bits of kits themselves that are susceptible to mutation, to a versatility discovered by chance.
There has been no mutation to a human-to-human form, and the occasional human case is due to proximity, not the sign of a pending mutation.
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