Sentence examples for mutations there is from inspiring English sources

"With certain BRCA mutations there is an increased risk of pancreatic cancer, prostate cancer," Yamada said.

But by experimenting with mutations there is a strong possibility they'll be able to cultivate hardier plants that can be farmed in northern Western Australia.

In addition to loss of chromosomal material and intragenic mutations there is a third mechanism, DNA methylation, which may have an important role in gene inactivation.

Interestingly, among the cell lines reported in the Sanger database to be positive for BRG1 mutations there is one neuroblastoma, a type of tumour that carry MYCN amplification at a very high frequency.

Our findings using the MD simulations demonstrate that in the presence of the mutations there is a relocation of the COOH-terminal region of factor VaKF and factor VaAA as compared with the wild-type cofactor molecule.

Because cancer results from the accumulation of multiple mutations, there is a possibility that the mutational makeup of a cancer cell will be comprised of some elements that create a pharmacological vulnerability, and others that, while functionally synergistic, could mask this vulnerability.

For all three patients with these mutations there was intrafamilial phenotypic heterogeneity, as well as differences from phenotypes reported in the literature.

Within the set of deleterious mutations there are n classes according to their effect size: those with deleterious effect s i arise at genomic rate U i. The combined deleterious rate across all mutations is ∑ i U i = U.

Alleles in white flowered types are represented by a restricted set of haplotypes; for the intron 6 splice donor site mutation there are just two haplotypes in the vicinity of the mutation (Fig. S3C).

In case 2, the cooperative lineage expansion case with early mutator mutation, there is no increase in fitness until a subset of oncogenic mutations have been acquired, at which point the fitness increases rapidly and lineage expansion begins.

Going back to cystic fibrosis: "In addition to those 196 mutations, there are another 6,800 bases [components of the gene] that could be mutated, so we would have to analyse how risky they are if we found a person with any of those mutations".