Sentence examples for mutations the expression from inspiring English sources

Even though the ligand-binding function was abolished by these two mutations, the expression of these mutants was normal at the protein level.

In order to identify additional molecular changes associated with the presence of β-galactosidase mutations, the expression of canine lysosomal multienzyme complex components in GLB1+/+, GLB1+/− and GLB1−/− fibroblasts was investigated by quantitative RT-PCR, Western blot and enzymatic assays.

Among the 12 cell lines with PTEN mutations, the expression of PTEN was observed in the HEC-116, HEC-88, HEC-151, and HEC-251 cell lines.

Owing to the double mutation, the expression level increased by 6-fold (Bmax=311 pmol/mg) in the membrane fraction of Pichia pastoris.

Indeed, in the strain without mutation, the expression threshold necessary to excision is very low.

Using a reporter protein downstream of the synthetic gene, allows the selection of clones with random mutations improving the expression or the folding of the protein of interest.

The csrS mutations enhanced the expression of scpC and slo, associated with the evasion of PMN functions and in vivo virulence.

Secondly, FGFR3 activating mutations alter the expression of several components of signaling pathways, possibly modifying the responsiveness to a number of other external stimuli.

The presence of the desired mutations in the expression constructs was verified by DNA sequencing.

Instead, we believe that these mutations affect the expression of genes flanking the transgene insertion site.

Five mutations prevent the expression of both the Secteur and Anneau, either spontaneously or after inoculation.